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Article
April 1934

CUTANEOUS REACTIONS WITH "PURIFIED" OIDIOMYCIN

Author Affiliations

Fellow in Dermatology and Syphilology, the Mayo Foundation, Rochester, Minn.; CINCINNATI

Work done in the Dermatologische Klinik, University of Zurich, Switzerland.

Arch Derm Syphilol. 1934;29(4):564-568. doi:10.1001/archderm.1934.01460100082007
Abstract

Oidia not only produce certain well known diseases of the skin but are often found on the normal skin, as Jessner and Kleiner,1 Staehelin, Mu and van Schouwen2 and others have shown. It is often difficult to decide whether the species of Oidia found in a particular case is pathogenic or only saprophytic. This question is of special interest since Ravaut and his school3 discussed levuroses and levurides, and since the investigations made by Ramel.4

Several methods have been used to differentiate between pathogenic and saprophytic strains of Oidia.5 For example, Staehelin, Mu and van Schouwen analyzed the cultures themselves. Benham,6 Hopkins and others have used agglutination as a differential criterion. There remains, among other methods, the clinical comparison of their oidiomycins.

Oidiomycin is a preparation which should be analogous to tuberculin and particularly to trichophytin. Intradermal testing of the latter preparations gives negative

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