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April 1934


Arch Derm Syphilol. 1934;29(4):612-615. doi:10.1001/archderm.1934.01460100130017

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Darier's Disease. Presented by Dr. Thomas Nisbet.  F. R., a white man, aged 31, states that in September, 1926, an erythematous eruption appeared suddenly on his abdomen. The eruption rapidly became generalized and assumed its present appearance.During the four years following the onset, the patient was treated in various naval hospitals and aboard ship, receiving a large number of injections of neoarsphenamine as well as local treatment, without result. He has had numerous Wassermann tests, all of which were negative.He presents a generalized eruption consisting of large papules covered with an adherent, greasy, gray crust. The scalp is covered with similar greasy scales.

DISCUSSION  Dr. C. R. Halloran: I have seen two patients with Darier's disease at the Los Angeles County General Hospital. I gave each patient a course of twenty injections of gold and sodium thiosulphate. One patient improved temporarily, but with further medication improvement did not

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