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Article
May 1934

ACANTHOSIS NIGRICANS: A CASE OF THE BENIGN FORM IN AN ADULT INVESTIGATED FROM THE ASPECT OF ENDOCRINE DYSFUNCTION

Author Affiliations

NEW YORK

From the New York Hospital and the Department of Medicine, Cornell University Medical College.

Arch Derm Syphilol. 1934;29(5):691-699. doi:10.1001/archderm.1934.01460110049007
Abstract

The case of acanthosis nigricans reported in this article occurred in a patient who was formerly under the care of one of us (H. J. S.) at the Memorial Hospital, New York, and who was transferred to the New York Hospital for study. At the latter institution work was directed particularly toward an investigation of the endocrine system in view of the hypotheses of Darier,1 Pollitzer2 and Porias3 concerning the etiology of acanthosis nigricans. Frequent clinical observations were made and these were supplemented by the laboratory procedures which are described following the report of the case. These procedures are arranged under the heading of the organ studied.

REPORT OF CASE 

History.—  A. de G., a white housewife, aged 46, was admitted to the New York Hospital on Oct. 26, 1932, because of itching growths on the skin and growths in the mouth of two years' duration. She

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