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Article
June 1934

PRACTICAL CLINICAL AND LABORATORY ASPECTS OF PRECIPITATION TESTS FOR SYPHILIS

Author Affiliations

SAN ANTONIO, TEXAS; GRAND RAPIDS, MICH.; CHICAGO

From the Section of Dermatology and the Serological Laboratory of the Department of Medicine, University of Chicago.

Arch Derm Syphilol. 1934;29(6):835-844. doi:10.1001/archderm.1934.01460120032003
Abstract

During the past ten years, precipitation tests for syphilis have been rapidly assuming a place of increasing importance in serodiagnosis. During this same period, the complement-fixation tests have also been undergoing modification and standardization. In clinical work the questions arise as to which tests to use and as to the relative reliance which may be placed on them. From the practical standpoint, any test must be judged by the following criteria: (1) sensitivity and specificity, (2) ease in reading results, (3) simplicity of performance (including the use of apparatus and biologic materials), (4) rapidity of performance and (5) the purpose for which the test is to be used. Obviously, a test which meets these requirements, is sufficiently sensitive and is easily performed will best meet the demands of the clinician. The amount of serum required for the test is sometimes also important, as in the case of infants.

Since the

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