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June 1934


Arch Derm Syphilol. 1934;29(6):962-966. doi:10.1001/archderm.1934.01460120159020

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A Case for Diagnosis. Presented by Dr. J. E. Fisher.  This white woman, aged 58, states that three weeks ago a sore developed on the right side of the upper lip which her family physician diagnosed as herpes simplex. The lesion did not follow the usual course of a herpetic process but refused to heal and became more extensive, with marked swelling of the upper lip and the right cheek. There is an area of sharply defined erythema almost the size of a palm on the right cheek, as well as marked enlargement of the submaxillary nodes, which are somewhat tender. The original lesion is approximately 2 cm. in diameter, is covered with a crust and extends onto the mucous membrane of the upper lip. On the adjacent surface of the mucous membrane of the lip there is a superficial ulcer about 1 cm. in diameter.General physical examination revealed

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