Many dermatologists have favorite combinations which from experience they have found to be of value.
Darier1 prepared the following compound which he considered practical not only for the skin but for the scalp:
He also used this soap mixture for the treatment of acne, but I received frequent complaints that it separated, and that it was for the most part unpleasant to use. There is no question that the use of soap as a local agent is necessary in the treatment of acne; the disadvantage of most soaps is that they are so irritating when applied directly to the skin that they are frequently discarded by patients who should use them.
To overcome these disadvantages, in 1932 the following formula, based on the aforementioned compound, was prepared; the prescription has the advantages of the soap mixture but none of its irritating qualities:
It is made in the following manner:
DOWNING JG. A NEW CLEANSING CREAM. Arch Derm Syphilol. 1934;30(2):243–244. doi:10.1001/archderm.1934.01460140069010
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