The present study has been undertaken as part of a general investigation of the influence of carbohydrate metabolism on the normal and on the diseased skin. As suggested in an earlier paper,1 it would seem probable that the final answer to the moot question among clinicians as to whether a high or low carbohydrate intake has any effect on the skin will be found in a more thorough understanding of the skin itself. It can be stated definitely that most dermatoses are not accompanied by any derangement of the carbohydrate metabolism of the patient, as indicated by studies of the blood sugar during fasting and dextrose tolerance.2 This evidence does not, in our opinion, answer the question as to whether there is any derangement of the carbohydrate metabolism of the normal or diseased skin of the patient.
This question has been the subject of an increasing number of
PILLSBURY DM, KULCHAR GV. THE DEXTROSE AND WATER CONTENT OF NORMAL AND OF INFLAMED SKIN. Arch Derm Syphilol. 1934;30(4):489–496. doi:10.1001/archderm.1934.01460160003001
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.