Ulcus vulvae acutum, originally described by Lipschütz,1 was considered by him to be a local infection with Bacillus crassus. Recently, Samek and Fischer,2 in a patient aged 19 who had ulcers within the vulva and an erythema nodosum-like eruption on the legs, demonstrated B. crassus bacteriologically, in cultures from the surface of ulcers and skin nodes and from the blood, and in histologic sections. Their interpretation was that of a general B. crassus infection with metastases to the skin.
Later Ito, Matras3 and Philadelphy4 obtained B. crassus both in smears and in culture from aphtha-like lesions on the mucosa of the mouth, concurrent with typical genital ulcers.
Thus, not only can B. crassus cause local ulcerations of the external genitalia, but the organism may be responsible for generalized infection, as is borne out by the first case to be reported here.
REPORT OF CASES
TALALOV DJZ. ULCUS VULVAE ACUTUM ACCOMPANIED BY DISEASE OF SKIN AND OF ORAL MUCOSA. Arch Derm Syphilol. 1934;30(4):510–516. doi:10.1001/archderm.1934.01460160024004
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