[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 52.200.130.163. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
October 1934

DANLOS SYNDROME ASSOCIATED WITH CONGENITAL LIPOMATOSIS

Arch Derm Syphilol. 1934;30(4):540-551. doi:10.1001/archderm.1934.01460160054008
Abstract

Margarot1 defined the Danlos syndrome as a tetrad of symptoms consisting of: (1) hyperelasticity of the skin; (2) hyperlaxity of the joints; (3) fragility of the skin, involving especially the exposed surfaces and prominences, and (4) pseudotumors following trauma. While isolated cases exhibiting one or more of the characteristics have been described, the complete syndrome rarely occurs. No cases have been reported in the American literature. The incomplete cases consisting of cutis laxa or hyperflexibility of the joints alone may be classified as formes frustes.

REPORT OF A CASE 

History.—  M. G., a white girl, aged 9, was admitted to the pediatric division of St. Mary's Hospital for a tonsillectomy. She weighed 45½ pounds (20.6 Kg.), and the pulse rate and temperature were normal.Birth was normal. She began to talk at 1½ years and walked at 2. Dentition appeared at 7 years. The child's intelligence was normal. She

×