The rare cutaneous manifestation of late syphilis first accurately described by Fournier1 under the name of "érythème circiné tertiaire," has been reported in about fifty cases of acquired syphilis.
F. Combes2 recently reported the condition in acquired syphilis, with histologic observations and a full review of the literature. Review of the available literature reveals no report of this type of eruption occurring as a manifestation of congenital syphilis. The eruption, as emphasized by Fournier, is a late (tertiary) manifestation, and has no relation to the early annular macular and annular papular eruptions not infrequently observed in recently acquired syphilis.
Unna3 studied the condition extensively, and this rare eruption of late syphilis is usually known as the neurosyphilid of Unna. The name, neurosyphilid, is probably inappropriate, as evidence (clinical or serologic) of syphilis of the central nervous system is often lacking.
The lesions of érythème circiné tertiaire, or
HALL TB, SCHAERRER H. NEUROSYPHILID OF UNNA AS A MANIFESTATION OF CONGENITAL SYPHILIS: FORME FRUSTE OF LATE CUTANEOUS SYPHILIS. Arch Derm Syphilol. 1934;30(4):561–565. doi:10.1001/archderm.1934.01460160075010
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