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In this book Essed vigorously combats the view of the American origin of syphilis. It is a work of scholarship and wide learning. His position is essentially as follows: He and his colleagues have never seen syphilis among the American Indians in Dutch Guiana, but frambesia tropica is common among them. He bases his own theory on the assumption that at the time of Columbus' first voyage conditions as regards these two diseases among the American Indians were as he and his colleagues found them among the Indians of Guiana now and maintains the thesis: "There was after the discovery of America a new disease imported into Europe by the sailors on the first voyage of Columbus. This new disease was the Framboesia Tropica."
Over den Oorsprong der Syphilis: Een kritisch-historisch-epidemiologische studie tevens ontwerp eener nieuwe theorie. Arch Derm Syphilol. 1935;31(2):287. doi:10.1001/archderm.1935.01460200131019