As nothing definitely has been proved to explain biologically the effect of roentgen rays on the human skin, it was decided to begin in this field of many theories by studying quantitatively, and as accurately as possible, the effect of the roentgen rays on the lipids of the human epidermis.
One fact that makes such a study logical is the striking reduction in the lipid content of carcinomatous tissue after roentgen therapy. Also, the findings of other observers on the blood cholesterol content following roentgen therapy have been rather startling. Malczyńsk1 noted a considerable rise of blood cholesterol during the two weeks following irradiation of areas of skin on the backs of dogs with either the ordinary roentgen rays or with the Grenz rays. Mader and Bingenheimer2 found that roentgen irradiation of mongolian idiots, whose blood cholesterol is low, as a rule, produces a rise in blood
WILE UJ, CAMERON OJ, ECKSTEIN HC. EFFECT OF THE ROENTGEN RAYS ON THE LIPIDS OF THE EPIDERMIS. Arch Derm Syphilol. 1935;32(1):69–72. doi:10.1001/archderm.1935.01470010072005
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