Clinical spectroscopy is a new method of attack in biologic research. This method has supplanted the usual analytic procedures by the use of an instrument that gives both qualitative and quantitative data in one analysis, namely, the spectrograph. The analysis of connective tissue for metallic constituents furnishes data of more clinical significance than the usual analysis of excretory products for toxic metals.1 As a means of identifying this test we coined the word "biospectrometric." By this term we designate a qualitative and quantitative analysis for the metallic constituents in differentiated and undifferentiated mesoderm. The dermal biopsy specimen is obtained with a 0.47 cm. punch and weighs approximately 0.025 Gm. The technic is as follows:
The site for taking the specimen is the area over the suprapatellar pad of fat because the samples are more uniform in quantity. This area is cleansed with an alcohol sponge. The central part, about
GAUL LE, STAUD AH. CLINICAL SPECTROSCOPYADVANTAGES AND PHYSICAL PRINCIPLES OF THE SPECTROGRAPH AND TECHNIC IN TAKING SPECIMEN FOR BIOSPECTROMETRIC ANALYSIS. Arch Derm Syphilol. 1935;32(3):385–393. doi:10.1001/archderm.1935.01470030027004
Customize your JAMA Network experience by selecting one or more topics from the list below.