Not infrequently a patient says that the condition of his skin has been attributed to "too much acid in the blood." When the patient is asked how the acidosis was discovered one usually finds that no laboratory test was made. This working hypothesis frequently provokes an interesting paradox: The physician tells the patient to avoid the "acid fruits," referring to the citrous fruits, which are known to have an alkaline ash.
To determine the presence of acidity the pH and carbon dioxide content of the blood serum were determined in patients with the following dermatoses: acne rosacea, acne vulgaris, angioneurotic edema, aphthous stomatitis, dermatitis medicamentosa, dermatomycosis, dermatitis venenata, dyshidrosis, erysipelas, erythema multiforme, keratosis senilis, lichen simplex chronicus, lingua geographica, lupus erythematosus, neurodermatitis, parapsoriasis, pityriasis rosea, prurigo nodularis, pruritus ani, pruritus vulvae, psoriasis, stasic eczema, stasic ulcer, sycosis vulgaris, tinea amiantacea, urticaria and vitiligo.
JULIUS E. GINSBERG. ACID IN THE BLOOD AS A CAUSE OF DISEASES OF THE SKIN. Arch Derm Syphilol. 1935;32(3):464–465. doi:10.1001/archderm.1935.01470030106011