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Pituitary Basophilism (Cushing) with Typical Changes in the Skin (Plethora, Adiposity, Purpuric Striae Atrophicae, Acrocyanosis and Hirsutism). Presented by Dr. J. Gardner Hopkins, New York.
Miss R. S., a Jewish woman aged 33, is presented from the Vanderbilt Clinic, with a condition of seventeen years' duration. She was admitted to the Vanderbilt Clinic in 1923 for treatment of verrucae. At that time most of the present signs were present but in a less marked degree than now.
The patient was presented by Dr. Paul Gross before the Section on Dermatology of the New York Academy of Medicine in April 1929 (Arch. Dermat. & Syph.21:480 [March] 1930), with the diagnosis of poikiloderma-like changes of the skin associated with symptoms suggestive of involvement of the pituitary gland, probably a tumor. After further study the case was described by Dr. Irving Pardee (Arch. Neurol. & Psychiat.31:1007 [May] 1934) as