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Scleroderma. Presented by Dr. J. Frank Fraser.
M. I., a woman aged 60, born in Germany, from the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital, was perfectly well until last August (nine months ago), at which time she was employed in a silk factory, her work consisting in washing the silk with "KO" cleaning fluid before it was fed to the machines for spinning. Her hands were constantly immersed in this cleaning fluid. In August 1934 she noticed that the skin of the right hand was becoming thick and tight. This disorder quickly spread to the entire body. The patient was hospitalized at the Bellevue Hospital one week for study.
There are marked hardening and thickening of the skin; the disorder affects almost the entire body and the face, but it is most pronounced on the hands, forearms and upper part of the