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Lupus Erythematosus Showing Features of Sarcoid, Resistant to Gold Sodium Thiosulfate But Responding to Bismuth Subsalicylate. Presented by Dr. Charles Albert Shumate for Dr. Harry E. Alderson.
This patient was presented at the meeting of this society in December 1934 with the diagnosis of lupus erythematosus resistant to therapy with a gold, but responding to treatment with a bismuth preparation (Arch. Dermat. & Syph. 32:311 [Aug.] 1935). At that time there was discussion as to whether the disorder was syphilis, sarcoid or lupus erythematosus. Serologic tests were negative; the history was irrelevant; the results of biopsy suggested lupus erythematosus. The treatment had consisted of nine intravenous injections of 5 mg. of gold sodium thiosulfate at weekly intervals, and during the period of treatment the eruption on the face became steadily worse. Injections of gold sodium thiosulfate were discontinued, and eight injections of 2 cc. of bismuth subsalicylate