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July 1936


Arch Derm Syphilol. 1936;34(1):156-160. doi:10.1001/archderm.1936.01470130159020

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A Case for Diagnosis. Presented by Dr. W. H. Connor.

C. C., a woman aged 48, from the service of Dr. Cole and Dr. Driver at the City Hospital, has secondary syphilis and received seventeen injections of mapharsen, or a total of 860 Gm., from June 1934 to Feb. 20, 1935. In addition, she received twenty-five intramuscular injections of bismuth subsalicylate. A few days after the final injection of mapharsen was given, there developed a generalized pruritic eruption simulating seborrheic dermatitis. The patient was given sodium thiosulfate intravenously and by mouth and seemed to improve. The administration of bismuth subsalicylate was then resumed. The eruption, however, persisted, a moderate exacerbation and partial remission taking place. The patient has been hospitalized since Aug. 9, 1935.

There is a widespread scaly eruption consisting of erythematous patches with scales. The lesions are round, vary in size from that of a 5 cent to

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