The therapy of scabies for many years has consisted of ointments containing sulfur, either alone or in combination with other drugs. The therapeutic action of sulfur apparently is dependent on the production of hydrogen sulfide, which is lethal to Acarus and its ova. Since its introduction by Ehlers1 in 1917, the so-called Danish treatment, which consists of the application of an ointment containing a combination of the high sulfides of potassium, has been more or less the standard therapy and for the most part it has been effective. Greenwood,2 however, has reported failure to alleviate the symptoms in 3.5 per cent of the patients treated by this method, as well as the occurrence of sulfur dermatitis in 2 per cent of the patients following the use of such an ointment. The disagreeable odor of sulfur and the necessity of keeping the body covered with ointment for twenty-four
KULCHAR GV, MEININGER WM. SODIUM THIOSULFATE IN TREATMENT OF SCABIES. Arch Derm Syphilol. 1936;34(2):218–219. doi:10.1001/archderm.1936.01470140026003
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