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To the Editor.—I wish to correct a seemingly serious ambiguity in my recently published paper on tryparsamide (Arch. Dermat. & Syph. 34:582 [Oct.] 1936). It appears that certain of my colleagues are laboring under the impression that I am advocating the use of tryparsamide alone in the primary stages of syphilis. This interpretation is as incorrect as it is difficult to understand, for in the summary of the aforementioned article I stated that tryparsamide has but a mediocre effect in suppressing early lesions. Indeed, the small amount of work done with the drug in cases of primary syphilis (two cases) indicates only too well that at the time the report was made the work was in the nature of an experiment which was undertaken with no small degree of trepidation. I merely advocated that tryparsamide be incorporated into the curriculum of the Cooperative Clinical Group as outlined for