Since the introduction of roentgen rays and radium epithelioma of the digits is not rare, but that of the palm is seldom met with, even less frequently than that of the sole. According to the statistics of Volkmann, von Brunn and Michael, which include 263 cases of epithelioma of the skin, in 19 cases the epithelioma affected the sole and in only 3 the palm.1 The chief interest in the case here reported, however, centers on the fact that the cancer developed at the site of a syphilitic lesion.
REPORT OF A CASE
In May 1906 I treated a woman aged 35 for an indeterminate dry scaliness of the right palm, which was surmised to be a localized eczema or possibly a manifestation of psoriasis but which, as events subsequently showed, was a squamous syphilid. Treatment for eczema brought about improvement, but the palm remained rough, dry and
Montgomery DW. EPITHELIOMA OF THE PALM DEVELOPING AT THE SITE OF A SYPHILITIC LESION. Arch Derm Syphilol. 1936;34(6):1024–1027. doi:10.1001/archderm.1936.01470180091009
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