Eczematous weeping eruptions and vesicular or bullous eruptions are uncommon forms of dermatitis due to the administration of arsenical compounds.1 The more usual eruptions are the zoster-like eruptions, those resembling lichen ruber planus, those of erythema multiforme type, the fixed exanthems due to arsphenamine and the well known exfoliative dermatitides. The vesicular and bullous lesions of this unusual type of arsenical dermatitis often terminate in pyoderma. This complication usually comes on during the apparent healing of the eruption and is rarely seen in bullous eruptions except when they are due to arsenic.2
MUIR KB. VESICULOBULLOUS DERMATITIS FOLLOWING ADMINISTRATION OF ARSPHENAMINE: REPORT OF A CASE. Arch Derm Syphilol. 1937;35(2):226–230. doi:https://doi.org/10.1001/archderm.1937.01470200026003
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