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The condition to be described resembles none described in the literature except the ``chlor-acne'' described by Prosser White. A preliminary report is made because of the fact that recently the use of the drugs under consideration was recommended for treatment of fungous infections in man.
Twenty-one cases have been observed. In seventeen the disorder was severe enough to require treatment. The patients treated were all young white men. Most of them were aged from 19 to 23; one was 34.
The chemicals which I later found to be causative were used in a mixture. The first acne-like eruption appeared one month after the products were manufactured in a powder form. All the men exhibiting the condition were employed in sacking the mixture. The disorder here described developed within the next six months after contact with the chemicals.
I have seen four laboratory workers who had a milder, more localized reaction
BUTLER MG. ACNEFORM DERMATOSIS PRODUCED BY ORTHO (2 CHLOROPHENYL) PHENOL SODIUM AND TETRA-CHLORPHENOL SODIUM. Arch Derm Syphilol. 1937;35(2):251–254. doi:10.1001/archderm.1937.01470200051006
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