In view of the frequency with which dietary revision is advised in cases of various pyogenic infections of the skin there exists a rather striking paucity of experimental evidence offering a rational basis for such procedures. Almost all the evidence indicating some association between carbohydrate metabolism and infection is based on observations made on diabetic patients. Many observers, including ourselves, have gained the impression in clinical work that nondiabetic patients with superficial infections of the skin are often found to have been taking excessive amounts of carbohydrates and that in some of these patients adjustment of the diet in this regard is a factor in the production of clinical improvement.
We know of no series of cases in which dietary methods of treatment have been employed exclusively in treating pyodermic infections,1 and this lack of adequate controls plus the necessarily somewhat impressionistic character of our
PILLSBURY DM, STERNBERG TH. RELATION OF DIET TO CUTANEOUS INFECTION: A STUDY OF THE INFLUENCE OF VARYING CARBOHYDRATE AND FAT INTAKES AND OF FASTING ON EXPERIMENTAL PYOGENIC CUTANEOUS INFECTIONS IN DOGS, WITH COMPARATIVE DETERMINATIONS OF THE GLYCOGEN CONTENT OF THE SKIN AND LIVER. Arch Derm Syphilol. 1937;35(5):893–909. doi:https://doi.org/10.1001/archderm.1937.01470230131007
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