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The existence of so-called precancerous stages and facts obtained in research concerning carcinogenic substances stimulated the authors to compare the behavior of verrucae, papillomas and carcinomas and to investigate their relations, analogies and transitions.
The subjects of their study were 1,480 school children and university students varying in age from 6 to 22 years and 1,300 patients examined at necropsy. Some of the conclusions they drew follow:
In man verruca vulgaris, verruca plana juvenilis, condyloma acuminatum and laryngeal papilloma are caused by a filtrable virus. This source is not yet established for papillomas of the eye, the mouth, the nose, the urethra and the external canal of the ear. In animals filtrable viruses play a rôle in the infectious papillomatosis of hares, the oral papillomatosis of dogs and the verrucae of cattle. Both in man and in animals verrucae and papillomas which are produced by a filtrable virus occur in
Warzen, Papillome und Krebs. Arch Derm Syphilol. 1937;36(1):245–246. doi:https://doi.org/10.1001/archderm.1937.01480010249030
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