Necrobiosis lipoidica diabeticorum (Urbach) is a curious fatty infiltration of the skin occurring only in persons with diabetes mellitus. The first case was described by Oppenheim>1 in 1928. His patient had lesions on the ventral and dorsal aspects of the lower extremities, on the upper extremities and on the trunk, buttocks, palms, soles and face. Earlier in the course of the disease the primary lesions were papules; later these became nodular plaques. The name "dermatitis atrophicans lipoides diabetica" was applied to this entity. Urbach>2 later described a similar condition; his patient showed lesions on the lower extremities which progressed from papules to nodules. He studied the rôle of lipids in various cutaneous conditions but did not arrive at a definite conclusion as to the amount of sterol or lipid present in cases of this disease.3 Additional cases were reported by Galewsky,4 Gottron,5 Balbi,6 Zeisler
BERNSTEIN JC. NECROBIOSIS LIPOIDICA DIABETICORUM (URBACH): COMPARISON WITH GRANULOMA ANNULARE. Arch Derm Syphilol. 1937;36(2):282–286. doi:10.1001/archderm.1937.01480020038004
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