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August 1937


Author Affiliations


From the Pathological Division, Bureau of Animal Industry, United States Department of Agriculture.

Arch Derm Syphilol. 1937;36(2):335-341. doi:10.1001/archderm.1937.01480020091014

During the spring months of 1936 among guinea-pigs procured for use in the laboratory from an establishment engaged in producing small animals a number were found which had cutaneous lesions on various parts of the body. These consisted of roughly circular, erythematous areas, scaling, sometimes encrusted and more or less depilated, occurring mostly about the head and face but also on occasion on other parts (fig. 1). The hairs at the periphery of the lesions were somewhat thinned and stood more erect than those on the surrounding normal skin. Within this zone the skin was faintly reddened. In most cases the lesions were 1 cm. or more in diameter, but some animals had smaller hemorrhagic encrusted foci, more or less widely disseminated, which gave a ragged appearance to the coat. It appeared that pruritis, if present, was not marked, as there was little or no scratching.

Microscopic study of scrapings

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