The term virulence indicates the degree of ability of pathogenic micro-organisms to produce infection. As experience has shown, this ability of a micro-organism to produce infection is not always the same in the end, and every pathogenic germ may be extremely virulent at times, while at other times it may exist as an entirely harmless parasite. Micro-organisms are extremely virulent as a rule after they have been transferred from one infected host where they have been able to produce a disease. However, when these germs are kept for a long time in artificial mediums, a gradual decrease of the virulence takes place, and their eagerness to fight is then slight. Virulent micro-organisms can be killed easily in vitro by any one of a number of chemical preparations. There is no proof as yet that it is possible to kill the germs by injecting antiseptic solutions into the living host. It
HALLAY LI. OLIGOSEPSIS. Arch Derm Syphilol. 1937;36(5):1008–1013. doi:10.1001/archderm.1937.01480050074009
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