Rendu1 and later Fiessinger and Rendu,2 French military surgeons, reported what they believed to be a new infection. It was subsequently named ectodermosis erosiva pluriorificialis.
The disease is characterized by an acute onset with fever and constitutional symptoms and a vesicular eruption involving notably the hands and feet, accompanied by an inflammation of some or all of the orifices—mouth, nose, conjunctiva, urethra, vagina and anus.
Some writers, notably the French, regard the disease as a clinical entity, whereas others believe it is one form of erythema exsudativum multiforme. Cases of ectodermosis erosiva pluriorificialis are herein reported—the first to be recorded under this name in English. The resemblance of the condition to the human form of foot and mouth disease is later discussed, as well as the different forms of erythema multiforme, of which ectodermosis erosiva pluriorificialis is regarded as one.
SYMPTOMS AND COURSE OF ECTODERMOSIS EROSIVA PLURIORIFICIALIS
KLAUDER JV. ECTODERMOSIS EROSIVA PLURIORIFICIALIS: ITS RESEMBLANCE TO THE HUMAN FORM OF FOOT AND MOUTH DISEASE AND ITS RELATION TO ERYTHEMA EXSUDATIVUM MULTIFORME. Arch Derm Syphilol. 1937;36(5):1067–1077. doi:10.1001/archderm.1937.01480050133020
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