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December 1937


Arch Derm Syphilol. 1937;36(6):1286-1304. doi:10.1001/archderm.1937.01480060159024

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A Case for Diagnosis (Ichthyosis Hystrix?). Presented by Dr. Fred Wise.  J. W., a boy aged 2 years, was first seen on Jan. 28, 1937, with an eruption on the trunk, the face and the extremities which had been present since birth. The patient was born with white skin which was thicker than normal. It was so itchy that from the first few months of life the hands had to be tied to prevent scratching. The skin has become more pigmented and thick, especially on the palms and the soles. There is no history of consanguinity in the family; four older sisters are living and well.The entire body except the face is covered with confluent brownish black hyperkeratotic lesions, which in places have been scratched off, showing erythematous areas; the underlying skin is coarser than normal. The eruption is more advanced on the palms and the soles than

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