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Article
January 1938

THE LEUKOPENIC INDEX TEST IN ATOPIC DERMATITIS

Author Affiliations

MINNEAPOLIS

From the Division of Dermatology, University of Minnesota, Dr. H. E. Michelson, Director; and the Dermatology Clinic, Minneapolis General Hospital, Dr. S. E. Sweitzer, Chief.

Arch Derm Syphilol. 1938;37(1):52-61. doi:10.1001/archderm.1938.01480070055007
Abstract

The leukopenic index test described by Vaughan1 was considered by him to be of value in discovering the offending food in certain allergic diseases. The test is made as follows: Two white blood cell counts are made at ten minute intervals while the patient is fasting; the patient then eats the food to be tested, and additional counts are made at fifteen minute intervals for the first hour, with a final count at the end of one and one-half hours. A mean is established between the two counts made during fasting. A drop of more than 1,000 cells below that point is considered a positive reaction; a drop of less than 1,000 cells, if it occurs in all or nearly all the counts, is also considered positive. A fluctuation of 1,000 above or below the mean is considered normal.

This test has been applied to patients with bronchial asthma,

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