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January 1938

A Study of the Allergic Metabolism Reaction in Isolated Tissues with Special Reference to Allergic Skin Affections

Arch Derm Syphilol. 1938;37(1):163-164. doi:10.1001/archderm.1938.01480070166021

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To read a volume of this sort is refreshing and fills one with enthusiasm. Whether the new reaction which the author describes will prove of practical value in dermatology is problematic. As the author points out, its determination is at present a complicated procedure. However, there is so much of value in this book that every dermatologist who is interested in the pathogenesis of cutaneous diseases, especially of those which are thought to be based on allergy, should read it.

The book is divided into two parts. In the first part the author carefully describes in simple and understandable language what he calls the tissue metabolism reaction. His test is based primarily on the work of Warburg. It is performed by a manometric method for determining the degree of lactic acid formation and respiration in isolated slices of tissue. By this method the anaerobic glycolysis and the respiration of the

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