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March 1938


Arch Derm Syphilol. 1938;37(3):534-542. doi:10.1001/archderm.1938.01480090163020

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Disseminated Xanthomatosis. Presented by Dr. Leo Spiegel.  J. S., a man aged 67, a native of England but a resident of the United States for the past thirty-nine years, came to the clinic of the Lenox Hill Hospital on Oct. 26, 1937. His eruption is of two years' duration and involves the entire face and neck, all the flexural surfaces (axillary, cubital, inguinal and popliteal) and the mucous membranes of the mouth. The lesions are discrete macules and papules, which vary in size from that of a pinhead to that of a pea or slightly larger and form small plaques in some areas. The macular lesions vary from dark red to purple, and the elevated papules and nodules are characteristic yellowish red and yellow. The lesions on the eyelids are numerous and interfere mechanically with the opening and closing of the eyelids. The patient complains of intense itching, although there

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