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May 1938


Arch Derm Syphilol. 1938;37(5):856-864. doi:10.1001/archderm.1938.01480110122012

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Asymptomatic Syphilis Associated with a Positive Wassermann and a Negative Laughlen Test. Presented by Dr. Louis Chargin.  P. G., a Negro aged 52, states that in 1918 he had a sore on the penis. He never received antisyphilitic treatment. Physical examination showed no abnormality. Examination of the blood on two occasions showed a 4 plus Wassermann reaction. The Laughlen test gave negative results on both occasions.

DISCUSSION  Dr. Louis Chargin: The purpose of presenting this patient is to point out the variance in results between the Wassermann test and the newly described precipitation test of Laughlen. My associates, Dr. Churg and Dr. Sobel, and I have been engaged recently in the study of this test. It is of great importance to discuss the Laughlen test because of the claims advanced, namely, that it is reliable and that it does not require a special laboratory but can be performed in

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