Recklinghausen's disease presents many variations in the localization and the intensity of the underlying pathologic process. It may remain stationary and limited to the cutaneous surface for many years, or it may be progressive at the outset and gradually involve the viscera and the central nervous system. The case to be described belongs to the latter category, and it presents some unusual localizations of neurofibromatous tumors.
REPORT OF A CASE
E. B., a man aged 21, for a number of years had multiple sessile tumors of various sizes, disseminated over the face, the trunk and the extremities. Six or seven years before examination an external deviation of the left eye developed. Soon afterward palsy of the peripheral type appeared on the left side of the face. Several months before examination he began to experience difficulty in walking, standing and turning while standing.At the time of examination some tumors were
GORDON A. DIFFUSE POLYMORPHOUS NEUROFIBROMATOSISWITH UNUSUAL LOCALIZATION AND INVOLVEMENT OF THE CENTRAL NERVOUS SYSTEM. Arch Derm Syphilol. 1938;37(6):983–986. doi:10.1001/archderm.1938.01480120049007