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A Case for Diagnosis (Pemphigus Vulgaris?). Presented by Dr. Frank C. Combes
A. P., a woman aged 53, a native of Norway, was reared on a farm where there was always an abundance of good food. Her menopause occurred suddenly about three months ago. Shortly thereafter her skin began to itch, and bullae developed and rapidly spread over her entire body. At present the eruption consists of numerous ruptured bullae, many of them arising from apparently normal skin. There is little itching, and no objective signs of scratching are noted. There are some burning and pain, particularly where the calamine lotion is "caked." At no time has she had any lesions of the buccal mucosa, although there have been two lesions on her face. The Nikolsky sign is absent. The urine is normal. The Wassermann reaction is negative. Her blood count showed moderate secondary anemia, with 11 per cent eosinophils.
Traub EF, Combes FC. NEW YORK DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1938;37(6):1070–1077. doi:10.1001/archderm.1938.01480120136023