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In this volume the authors present an analysis of the cerebrospinal fluids examined by them since 1926 and show the value of examination of the spinal fluid in differentiating diseases of the central nervous system. They made careful studies of the normal as well as the pathologic physiology. An important feature of their investigations was the examination of the fluid in relation to the stage of the disease process, as they found that a given change in the fluid has a different clinical significance in the early stages than it has in the terminal stages of a disease. They stress the importance of measurements of pressure, a procedure too frequently neglected.
The results of examination of 21,000 specimens of fluid furnish the working basis of their report, which is divided into eight chapters with the following headings: (1) "Historical Data"; (2) "Anatomy and Physiology"; (3) "Chemistry and Pathologic Physiology"; (4)
The Cerebrospinal Fluid. Arch Derm Syphilol. 1938;37(6):1095. doi:10.1001/archderm.1938.01480120161029
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