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Severe Ichthyosis. Presented by Dr. Howard Fox.
M. R., a girl aged 20, a student, has suffered from an eruption since she was a few weeks old. No member of her family has ever been similarly affected. The eruption involves the entire cutaneous surface with the exception of the palms and the soles. The skin is dry, scaly and thickened and in places shows the tesselated appearance characteristic of ichthyosis. In some areas it presents the appearance of dermatitis exfoliativa. The patient is of medium size and weight, has always enjoyed excellent health and was valedictorian of her class in high school. The skin, especially that of the lower extremities, is slightly reddish. There are no dystrophic changes in the nails. The Wassermann reaction was negative, and other laboratory tests previously performed showed nothing abnormal except that the basal metabolic rate was + 41 and + 43 per cent on two determinations.
Traub EF, Combes FC. NEW YORK DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1938;38(1):87–106. doi:10.1001/archderm.1938.01480130090015
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