Since citrus fruits are becoming more and more an integral part of the everyday diet and so-called sensitivity to these fruits is developing into a common problem,1 it is our purpose to correlate the pertinent literature on this subject. Allergy to the fruit is certainly not the only factor that is important in a given case, and we shall attempt to demonstrate that many of the so-called manifestations of allergy are found, when analyzed, to be pseudoallergic reactions due to contaminants, to dyestuffs or to some cause entirely unrelated to citrus fruits.
Cutaneous and other diseases have been ascribed to citrus fruits for a long time. Bazin2 in 1862 described dermatitis of the face and upper extremities in orange peelers. In 1887 White,3 of Boston, called attention to citrus fruit dermatitis and pointed out that it did not occur in southern California because marmalade was not made
BEERMAN H, FONDÉ GH, CALLAWAY JL. CITRUS FRUIT DERMATOSES. Arch Derm Syphilol. 1938;38(2):225–234. doi:10.1001/archderm.1938.01480140065008
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