There is general recognition of the important role played by contact and environmental allergens in the production of eczema in adults. Only during the past few years have advances been made in the study of these factors in eczema of infants and children. Because we have long been convinced of the importance of these factors in the etiology of eczema of infants and children, we feel that the results of our studies should be of value.
"CONGENITAL ALLERGY" IN CONTACT DERMATITIS
The literature still contains occasional references to "congenital allergy," as applied to contact dermatitis, notwithstanding the fact that most writers in recent years have expressed the opinion that one inherits not specific epidermal sensitivity but a predisposition or tendency to such sensitivity. A careful survey of the literature indicated that no observer had applied patch tests with common eczema-producing substances to a series of newborn infants. Straus1
OSBORNE ED, WALKER HL. CONTACT AND ENVIRONMENTAL ALLERGENS AS A CAUSE OF ECZEMA IN INFANTS AND IN CHILDREN. Arch Derm Syphilol. 1938;38(4):511–525. doi:10.1001/archderm.1938.01480160003001