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Article
November 1938

TABES DORSALIS: COOPERATIVE CLINICAL STUDIES IN THE TREATMENT OF SYPHILIS

Author Affiliations

ROCHESTER, MINN.; CLEVELAND; BALTIMORE; PHILADELPHIA; ANN ARBOR, MICH.; WASHINGTON, D. C.

From the clinics for patients with syphilis of the Mayo Clinic, Western Reserve University, Johns Hopkins University, University of Pennsylvania and University of Michigan, assisted by the U. S. Public Health Service, with the financial support of an anonymous donor.

Arch Derm Syphilol. 1938;38(5):692-704. doi:10.1001/archderm.1938.01480170016002
Abstract

This is an abstract of a study1 of the treatment of tabes dorsalis and is the second of a series of reports on neurosyphilis prepared by the Cooperative Clinical Group. The material for this report was gathered from the five cooperating clinics, which created a pool of reports concerning 75,000 patients who had syphilis. In this mass of material were represented 5,293 patients whose spinal fluid had been examined more than once; 40 per cent of these manifested clinical evidence of neurosyphilis, and the reaction of their spinal fluid was positive. The records of 985 patients from this group who had tabes dorsalis form the basis for this report. These patients were treated and observed in one of the clinics for not less than two years, the periods of observation ranging from two to twenty years.

The diagnosis of tabes dorsalis was based on the following subjective and objective

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