This is an abstract of a study1 of the treatment of tabes dorsalis and is the second of a series of reports on neurosyphilis prepared by the Cooperative Clinical Group. The material for this report was gathered from the five cooperating clinics, which created a pool of reports concerning 75,000 patients who had syphilis. In this mass of material were represented 5,293 patients whose spinal fluid had been examined more than once; 40 per cent of these manifested clinical evidence of neurosyphilis, and the reaction of their spinal fluid was positive. The records of 985 patients from this group who had tabes dorsalis form the basis for this report. These patients were treated and observed in one of the clinics for not less than two years, the periods of observation ranging from two to twenty years.
The diagnosis of tabes dorsalis was based on the following subjective and objective
O'LEARY PA, COLE HN, MOORE JE, et al. TABES DORSALIS: COOPERATIVE CLINICAL STUDIES IN THE TREATMENT OF SYPHILIS. Arch Derm Syphilol. 1938;38(5):692–704. doi:10.1001/archderm.1938.01480170016002
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