Laboratory methods for the detection and identification of fungi pathogenic to man are time consuming and sometimes difficult to carry out, and the results are frequently inconclusive. The technical details and the interpretation of the microscopic and cultural results all require experience, patience and judgment. For these and other reasons, the development of a cutaneous test of diagnostic specificity would be of considerable importance in the recognition of mycotic diseases. A great deal of work relating to this subject has been carried out since 1902, when Neisser1 and Plato made an extract of fungi isolated from patients with ringworm and called the product "trichophytin." Nevertheless, there are considerable confusion and differences of opinion as to the value of fungus vaccines in diagnosis and treatment. The Council on Pharmacy and Chemistry of the American Medical Association2 has twice postponed consideration of the efficacy of fungus extracts. A study of
LEWIS GM, MacKEE GM, HOPPER ME. THE TRICHOPHYTIN TEST: ITS VALUE AS A DIAGNOSTIC AID. Arch Derm Syphilol. 1938;38(5):713–726. doi:10.1001/archderm.1938.01480170037004
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