Michael1 has reviewed the subject of acne fully; however, he left open the discussion as to causation by factors now unknown. Among the causes considered he referred to the work of von Kemeri2 and of Ramel2a on tuberculosis and its relation to acne.
Because certain acneform eruptions did not respond to the usual methods of treatment of acne, I was prompted to perform tuberculin tests in many cases of obstinate involvement and followed these tests with administration of tuberculin as a therapeutic measure. Later, routine tuberculin tests were made on all patients with cystic acne who were free of pyogenic infections or menstrual disturbances.
Michelson and Winer3 reviewed tuberculodermas of the face and classified them. In conclusion they stated:
In reviewing the forms of tuberculosis which may occur on the face we believe that the variations in the clinical findings and the similarities in the histologic
VAN STUDDIFORD MT. DIAGNOSTIC AND THERAPEUTIC USE OF TUBERCULIN IN CERTAIN ACNEFORM ERUPTIONS. Arch Derm Syphilol. 1938;38(5):737–745. doi:10.1001/archderm.1938.01480170061006
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