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February 1939


Author Affiliations
Montreal, Canada.
Arch Derm Syphilol. 1939;39(2):349. doi:10.1001/archderm.1939.01480200156016

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To the Editor:—  I wish to comment on the recent report of Drs. G. D. Astrachan and A. G. Franks (Arch. Dermat. & Syph.38:949 [Dec.] 1938).These authors stated that only 2 cases of nitritoid reaction following an injection of tryparsamide have been reported. In the British Journal of Venereal Diseases (10:99 [April] 1934) I briefly reported a case of severe nitritoid reactions to tryparsamide. I observed a second case of such reactions in my private practice in 1936. This case has been reported in the Queries and Minor Notes of The Journal of the American Medical Association (106:1224 [April 4] 1936). At the present time I have under my care in the syphilis clinic of the Royal Victoria Hospital a third patient who has suffered from typical nitritoid reactions.

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