In 1932 Ludy1 reported 6 successive cases of pemphigus in which the condition was apparently cured by large doses of viosterol and ultraviolet ray therapy. His results led to the trial of concentrated viosterol in this case.
REPORT OF A CASE
Dr. E. L. A., a white man aged 65, married, a college president, was first seen June 11, 1936. The chief complaint was a pruritic, painful erythematobullous eruption completely covering the feet, the legs, the lower parts of the thighs, the hands and the forearms. It consisted of widely separated, discrete lesions on the upper parts of the thighs, the hips, the back, the arms, the shoulders, the upper part of the chest, and the neck. The face, scalp, abdomen and mucous membranes were not involved. The prevailing lesions were bullae 1 to 3 cm. in diameter, situated on erythematous bases. A few bullae appeared without the erythematous
KING H, HAMILTON CM. PEMPHIGUS CONTROLLED BY VITAMIN D. Arch Derm Syphilol. 1939;39(3):515–517. doi:10.1001/archderm.1939.01480210130014
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.