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April 1939


Author Affiliations


From the Department of Dermatology and Syphilology of the College of Medicine of the University of Cincinnati.

Arch Derm Syphilol. 1939;39(4):696-704. doi:10.1001/archderm.1939.01480220081008

While the syndrome of progressive atrophy of the face has been of interest chiefly to neurologists and has been studied extensively by them, it concerns the dermatologists as well. The dermatologists' reports have been concerned with the relation of this disorder to scleroderma. The confusion existing among neurologists regarding its association with scleroderma would be helped by a combined neurologic and dermatologic study. Unfortunately, this has not been attempted, and in many cases one must rely on inadequate descriptions. The other clinical condition related to hemiatrophia faciei progressiva is lipodystrophia progressiva (Simon's disease).

More than 400 cases of various stages of progressive hemiatrophy have been reported. The best recent review of the entire subject is the complete one of Archambault and Fromm.1 These authors also presented 3 new cases. Cases recently reported by American dermatologists include those of Levin,2 Osborne,3 Boardman,4 Tobias,5 Eller,6 O'Leary and