The use of mapharsen to terminate malaria artificially produced by inoculation in the treatment of neurosyphilis in a series of 24 cases was recently reported by Goldman.1 While it was recommended that to insure against recurrences three or four injections should be given, it was stated that in over 90 per cent of the cases a single injection sufficed to terminate the malaria permanently.
As a result of our experience in treating patients inoculated therapeutically with the organisms of tertian malaria, as were Goldman's, we are heartily in accord with his recommendation that three or four injections should be given to insure against recurrences. We are inclined to believe that more are advisable.
In a series of 9 consecutive patients treated by the Section of Venereal Disease Control of the British Columbia Provincial Board of Health in Vancouver, one injection of 0.04 to 0.06 Gm. of mapharsen was given,
Cleveland DEH, Turvey SEC. USE OF MAPHARSEN FOR TERMINATING MALARIA ARTIFICIALLY PRODUCED BY INOCULATION. Arch Derm Syphilol. 1939;39(6):1043–1044. doi:10.1001/archderm.1939.01480240091014
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