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August 1939


Arch Derm Syphilol. 1939;40(2):326-333. doi:10.1001/archderm.1939.01490020153025

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Small Cell Carcinoma of Cervical Nodes—Primary Site Unknown. Acanthosis Nigricans. Presented by Dr. Frank McDonald (from the Department of Dermatology and Syphilology, Lakeside Hospital).  R. M., a housewife aged 64, entered Lakeside Hospital in 1933 for cholecystitis, substantiated by roentgen examination, and was treated by cholecystomy. One year ago nonpainful swellings appeared behind both ears and slowly increased in size, especially the one in the right posterior cervical region. As the lumps enlarged there was accompanying pain. Histologic examination of a node from the right posterior cervical chain was reported as showing small round cell carcinoma. During April and May, 1938, on the advice of the department of roentgen therapy, the patient was given six roentgen treatments. The condition did not change, and five months ago a generalized eruption appeared. The face, postauricular area, neck, hands, wrists, the areas along the vertebral column, under the breasts and back of the

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