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September 1939


Arch Derm Syphilol. 1939;40(3):390-396. doi:10.1001/archderm.1939.01490030047007

Histiocytomas are well known solid tumors of the skin. Formerly they were believed to be hard fibromas. Worringer and Kwialkowski1 stated that the term histiocytoma was not found in the classification of cutaneous tumors because these nodules were erroneously diagnosed. Owing to the work of Worringer and others it is now believed that some of them at least are characterized by proliferation of histiocytes. Many illustrations of these benign neoplasms have appeared in the recent literature. Senear and Caro2 reported a series of cases, proving the tumors to be of histiocytic origin. They injected colloidal substances and demonstrated their presence in the cells. Histiocytomas may arise spontaneously or follow trauma. The familiar lipoid xanthoma usually follows trauma. Lewis and Sachs3 reported a peculiar mixed histiocytoma containing lipoids which had followed an injury. Diss4 reported a histiocytoma containing lipoid material and hemosiderin. The literature contains many examples