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September 1939


Author Affiliations


From the Johns Hopkins Medical School, Department of Dermatology.

Arch Derm Syphilol. 1939;40(3):422-432. doi:10.1001/archderm.1939.01490030079012

In 1931, Mashkilleisson1 presented an excellent review of epidermodysplasia verruciformis, describing in detail a patient with the generalized form of the disease and reporting briefly on a patient with the localized type. This form of dysplasia was first described in 1922 by Lewandowsky and Lutz2 and was reported in the same year by Fuchs.3 Table 1 is a modified summary of the cases included in Mashkilleisson's review. Mashkilleisson1 stated that the disease was a hereditary dystrophy with a precancerous tendency, because in 20 per cent of the cases previously reported there were cutaneous epitheliomas. The question of whether epidermodysplasia verruciformis is a definite entity or a special type of generalized warts, a view championed by Hoffmann,4 has not been settled. Epidermodysplasia verruciformis has been reported under the following titles: verrucosis generalisata,5 verrucae dyskeratoticae congenitales,6verallgemeinerte Warzenerkrankung, 4 verrucae disseminatae,7warzigen Naevi

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